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Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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Targeting TLR/IL-1R signalling in human diseases

Maria Loiarro1, Vito Ruggiero, Claudio Sette

  • 1Department of Public Health and Cell Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.

Mediators of Inflammation
|April 17, 2010
PubMed
Summary

Toll-like receptor/interleukin (IL)-1 receptor (TLR/IL-1R) superfamily proteins are key in immune responses. Inhibitors targeting TLR/IL-1R signaling show promise for treating inflammatory and autoimmune diseases.

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