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Related Experiment Video

Updated: Jun 13, 2026

Screening People on Standing Balance with Romberg Testing and Walking Balance with Tandem Walking

Screening People on Standing Balance with Romberg Testing and Walking Balance with Tandem Walking

Published on: September 1, 2023

Relationship between essential tremor and cerebellar dysfunction according to age.

Eui-Seong Lim¹, Man-Wook Seo, Seong-Ryong Woo

¹Department of Neurology, Chonbuk National University College of Medicine, Jeonju, Korea.

Journal of Clinical Neurology (Seoul, Korea)

|April 17, 2010

Summary

Essential tremor (ET) patients exhibit impaired tandem gait, suggesting cerebellar dysfunction. This gait abnormality is more pronounced in older ET individuals, highlighting aging

Keywords:

Age Cerebellum Essential tremor Tandem gait

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Area of Science:

Neuroscience
Neurology
Movement Disorders

Background:

The cerebellum's role in essential tremor (ET) pathophysiology is widely suspected.
Investigating the link between ET and cerebellar dysfunction is crucial for understanding the disorder.

Purpose of the Study:

To determine if cerebellar dysfunction, assessed via tandem gait, is associated with essential tremor.
To explore the influence of age on the relationship between ET and gait abnormalities.

Main Methods:

Tandem gait test involving a ten-step walk was administered to 41 ET patients and 44 controls.
Missteps during the tandem walk were meticulously counted for each participant.
Statistical analyses, including sex-adjusted odds ratios and age stratification, were performed.

Main Results:

ET patients demonstrated a significantly higher number of missteps during tandem gait compared to controls.
A tandem gait abnormality was associated with ET, with an odds ratio of 3.40.
Older ET patients (age ≥70) exhibited a higher prevalence of tandem gait abnormality than younger patients.

Conclusions:

Cerebellar neural circuitry dysfunction may contribute to the pathophysiology of essential tremor.
Aging appears to be a significant factor that modifies the association between cerebellar dysfunction and ET.