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Updated: Jun 13, 2026

One-anastomosis Gastric Bypass (OAGB) in Rats
Published on: November 10, 2018
Incidence and risk factors for the development of anemia following gastric bypass surgery
Dimitrios V Avgerinos1, Omar H Llaguna, Matthew Seigerman
1Department of Surgery, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, NY 10003, United States.
Aim:
To evaluate the incidence and risk factors for the development of anemia after Roux-en-Y gastric bypass (RYGB).
Methods:
A retrospective analysis of patients undergoing RYGB from January 2003 to November 2007 was performed. All patients had a preoperative body mass index > 40 kg/m(2). A total of 206 patients were evaluated. All patients were given daily supplements of ferrous sulfate tablets for 2 wk following their operation. Hematological and metabolic indices were routinely evaluated following surgery. Patients were followed for a minimum of 86 wk.
Results:
There were 41 males and 165 females with an average age of 40.8 years. 21 patients (10.2%) developed post-operative anemia and 185 patients (89.8%) did not. Anemia was due to iron deficiency in all cases. The groups had similar demographics, surgical procedure and co-morbidities. Menstruation (P = 0.02) and peptic ulcer disease (P = 0.01) were risk factors for the development of post-operative anemia.
Conclusion:
Iron deficiency anemia is frequent. RYGB surgery compounds occult blood loss. Increased ferrous sulfate supplementation may prevent iron depletion in populations at increased risk.
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