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Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

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Related Experiment Video

Updated: Jun 13, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

[Retinal vein occlusion].

E Héron1

  • 1Service de médecine interne, Centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75571 Paris cedex 12, France. heron@quinze-vingts.fr

La Revue De Medecine Interne
|April 20, 2010
PubMed
Summary
This summary is machine-generated.

Retinal vein occlusion (RVO) causes painless vision loss and is a leading cause of blindness. While its exact cause is unknown, RVO is linked to hypertension and glaucoma, increasing stroke risk.

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In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
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Last Updated: Jun 13, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
07:35

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

Published on: April 21, 2022

Area of Science:

  • Ophthalmology
  • Vascular Medicine

Context:

  • Retinal vein occlusion (RVO) affects over 1% of individuals older than 40.
  • It presents as painless unilateral vision loss, often leading to significant visual impairment.
  • RVO is a major cause of unilateral blindness.

Purpose:

  • To summarize the current understanding of Retinal Vein Occlusion (RVO).
  • To highlight diagnostic features, associated conditions, and potential complications of RVO.

Summary:

  • RVO involves blockages in retinal veins, impacting central or branch vessels.
  • Diagnosis is typically made via fundus examination showing hemorrhages, edema, and venous dilation.
  • While associated with hypertension and glaucoma, RVO is not linked to thrombophilia or cancer.

Impact:

  • RVO increases the risk of ischemic neurovascular events, particularly in younger patients.
  • Macular edema and neovascularization are common complications.
  • Current treatments include pan-retinal photocoagulation and intravitreal corticosteroid injections for macular edema.