Related Experiment Video
Updated: Jun 13, 2026

Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
Published on: April 13, 2015
Telomere biology of the chicken: a model for aging research
Susan E Swanberg1, Thomas H O'Hare, Elizabeth A Robb
1Department of Animal Science, University of California, One Shields Avenue, Davis, CA 95616, United States. seswanberg@ucdavis.edu
Abstract:
Division-dependent telomere shortening correlating with age triggers senescence on a cellular level and telomere dysfunction can facilitate oncogenesis. Therefore, the study of telomere biology is critical to the understanding of aging and cancer. The domestic chicken, a classic model for the study of developmental biology, possesses a telomere genome with highly conserved aspects and distinctive features which make it uniquely suited for the study of telomere maintenance mechanisms, their function and dysfunction. The purpose of this review is to highlight the chicken as a model for aging research, specifically as a model for telomere and telomerase research, and to increase its utility as such by describing developments in the study of chicken telomeres and telomerase in the context of related research in human and mouse.
Related Concept Videos
Telomeres and Telomerase
Telomeres and Telomerase
Replication in Eukaryotes
Many Proteins Orchestrate Replication at the Origin
Eukaryotic replication follows many of the same...
Replication in Eukaryotes
Replicative Cell Senescence
Replicative Cell Senescence

