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Published on: April 19, 2014
Monomethylamine as a nitrogen source for a nonmethylotrophic bacterium, Agrobacterium tumefaciens
Yin Chen1, Kathryn L McAleer, J Colin Murrell
1Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom.
Abstract:
Monomethylamine can be used by nonmethylotrophs as a sole nitrogen source but not as a carbon source; however, little is known about the genes and enzymes involved. The gamma-glutamylmethylamide/N-methylglutamate pathway for monomethylamine utilization by methylotrophs has recently been resolved. We have identified genes encoding key enzymes of this pathway in nonmethylotrophs (e.g., Agrobacterium tumefaciens) and demonstrated that this pathway is also involved in the utilization of monomethylamine as a nitrogen source by nonmethylotrophs.
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