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Published on: July 24, 2016
Is neonatal antiretroviral therapy a risk factor for NEC occurrence?
Maria Pia De Carolis1, Serafina Lacerenza, Daniele De Luca
1Division of Neonatology, Department of Pediatrics, University Hospital "A. Gemelli" Catholic University of the Sacred Heart, Rome, Italy.
Abstract:
An association between maternal human immunodeficiency virus (HIV) infection and increased necrotizing enterocolitis (NEC) risk has been reported. Viral exposure and maternal antiretroviral therapy have been described as mediators of this risk. We report a preterm patient with delayed meconium passage and subsequent NEC, in which both the above-mentioned mechanisms were excluded, suggesting that neonatal antiretroviral therapy could be the most relevant risk factor for NEC in a susceptible preterm gut.
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