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Identification of a novel HLA-Cw*15 variant allele, Cw*1526

D Wang1, Z Deng

  • 1Immunogenetics Laboratory, Shenzhen Blood Center, Shenzhen, Guangdong, China. riverch418@hotmail.com

Tissue Antigens
|April 21, 2010
PubMed

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Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...