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Updated: Jun 13, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Cross-sectional relations of lipid concentrations to left ventricular structural attributes
Raghava S Velagaleti1, Michael J Pencina, Ramachandran S Vasan
1National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
None:
Although previous investigations reported on the associations of lipid concentrations with left ventricular remodeling in specific subpopulations, few data exist on these associations in a community-based sample of subjects without cardiovascular disease. In this study, 3,554 Framingham Heart Study participants (mean age 47 years, 53% women) without preexisting clinical cardiovascular disease were examined, and no meaningful associations of high-density lipoprotein cholesterol or non-high-density lipoprotein cholesterol with echocardiographic indexes of left ventricular structure were observed. In conclusion, these data do not support an independent association between lipid concentrations and left ventricular structure.
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