Related Experiment Video
Updated: Jun 13, 2026
08:26
Live Imaging of Drug Responses in the Tumor Microenvironment in Mouse Models of Breast Cancer
Published on: March 24, 2013
Imaging breast cancer chemotherapy response with light. Commentary on Soliman et al., p. 2605
Bruce J Tromberg1, Albert E Cerussi
1Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92715, USA. bjtrombe@uci.edu
Abstract:
Diffuse optical spectroscopy (DOS), which is used to image tumor metabolic response to neoadjuvant chemotherapy (NAC), shows large changes in tumor functional parameters with significant reductions in oxy- and deoxyhemoglobin for responders versus nonresponders. Although investigational, DOS may provide a cost-effective, risk-free method for optimizing NAC drug and dosing strategies for individual patients.
