Evaluation of infants and children with refractory lower respiratory tract symptoms

Bradley E Chipps1

  • 1Capital Allergy and Respiratory Center, Sacramento, California 95819, USA. bchipps@capitalallergy.com

Insights

Recurrent wheezing in young children often leads to an asthma diagnosis. If asthma treatment fails, consider other conditions like reflux or cystic fibrosis for accurate diagnosis and management.

Area of Science:

  • Pediatric Pulmonology
  • Diagnostic Medicine

Background:

  • Recurrent wheezing is a common presentation in young children.
  • Asthma is frequently diagnosed, but treatment is not always effective.

Purpose of the Study:

  • To outline diagnostic considerations for recurrent wheezing in children.
  • To identify differential diagnoses when asthma therapy is unsuccessful.

Main Methods:

  • Literature review.
  • Analysis of 30 years of clinical experience.

Main Results:

  • Initial workup includes asthma risk factors and symptom assessment.
  • Consider gastroesophageal reflux, protracted bacterial bronchitis, tracheobronchomalacia, and cystic fibrosis if asthma treatment fails.
  • Perform appropriate diagnostic testing for these conditions.

Conclusions:

  • In young children with recurrent lower airway symptoms and a negative modified Asthma Predictive Index, consider these alternative diagnoses.
  • A systematic diagnostic approach is crucial for effective management.
Abstract

Related Concept Videos

Assessment of Respiration01:23

Assessment of Respiration

The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
2.1K
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.9K
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
3.9K
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
534
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
971
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
845