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Updated: Jun 13, 2026
06:35
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
[Polymyalgia rheumatica and giant cell arteritis: what's new?]
Michael J Nissen1, Cabay Gabay
1Service de rhumatologie, Département de médecine interne, HUG, 1211 Genève 14. michael.j.nissen@hcuge.ch
Revue Medicale Suisse
|April 23, 2010
Summary
Polymyalgia rheumatica (PMR) and temporal arteritis (TA) require prompt diagnosis and corticosteroid treatment to prevent severe complications. Early intervention and monitoring are key for managing these elderly patient conditions.
Area of Science:
- Rheumatology
- Geriatric Medicine
- Internal Medicine
Context:
- Polymyalgia rheumatica (PMR) and temporal arteritis (TA) are prevalent in elderly populations.
- These conditions necessitate prompt diagnosis and treatment to avert serious complications.
Purpose:
- To outline the diagnostic approaches and critical management strategies for PMR and TA.
- To emphasize the importance of early corticosteroid therapy and ongoing monitoring.
Summary:
- Diagnosis of PMR is primarily clinical, while TA requires clinical and histopathological confirmation.
- Imaging modalities like ultrasound and PET-CT may aid diagnosis in specific cases.
- Intravenous corticosteroids are beneficial for TA, especially with visual symptoms. Methotrexate may reduce corticosteroid dependency.
- Monitoring for aortic aneurysms and large vessel involvement is crucial.
Impact:
- Facilitates timely and accurate diagnosis of PMR and TA in elderly patients.
- Guides effective treatment strategies, including corticosteroid use and potential adjunctive therapies.
- Highlights the necessity of long-term follow-up to manage potential systemic complications.
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