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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
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Published on: May 10, 2012

Applying functional MRI to the spinal cord and brainstem.

Jordan K Leitch1, Chase R Figley, Patrick W Stroman

  • 1Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.

Magnetic Resonance Imaging
|April 23, 2010
PubMed
Summary

Functional magnetic resonance imaging (fMRI) of the spinal cord (SC) visualizes neural activity. Despite challenges, spinal fMRI shows promise for clinical applications in spinal cord injury and other neurological conditions.

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Area of Science:

  • Neuroimaging
  • Spinal Cord Research
  • Functional MRI

Background:

  • Spinal fMRI enables noninvasive visualization of neural activity in the spinal cord and brainstem.
  • Widespread clinical adoption of spinal fMRI is limited by technical challenges and narrower applications compared to brain fMRI.
  • Significant methodological advancements have been made in spinal fMRI techniques.

Purpose of the Study:

  • To review the progress and potential applications of spinal fMRI.
  • To highlight the utility of spinal fMRI in studying neurological conditions.
  • To emphasize the clinical translation of spinal fMRI for patient assessment and monitoring.

Main Methods:

  • Review of existing literature on spinal fMRI studies.
  • Analysis of spinal fMRI applications in sensory and motor task paradigms.
  • Case study of spinal fMRI in a spinal cord injury patient with a metallic fixation device.

Main Results:

  • Spinal fMRI has yielded consistent and sensitive results in patient populations with spinal cord injury (SCI), multiple sclerosis (MS), and neuropathic pain (NP).
  • Successful application of spinal fMRI in a SCI patient with a metallic fixation device demonstrates progress towards clinical utility.
  • Consistent findings across studies suggest broad applicability of spinal fMRI using standard MRI systems.

Conclusions:

  • Spinal fMRI is a rapidly advancing technique with significant potential for clinical application.
  • The technique shows promise for supplementing behavioral assessments and providing insights into SC function in injured and diseased individuals.
  • Further implementation in clinical settings is expected to support the development of novel treatment and monitoring strategies for SC conditions.