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Related Concept Videos

Oogenesis02:07

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Nondisjunction01:21

Nondisjunction

Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold sister...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Ovarian Cycle01:27

Ovarian Cycle

The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle length...

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Related Experiment Video

Updated: Jun 13, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Fibroids and reproduction.

David L Olive1, Elizabeth A Pritts

  • 1Wisconsin Fertility Institute, Middleton, Wisconsin 53562, USA. lapskyboy@aol.com

Seminars in Reproductive Medicine
|April 24, 2010
PubMed
Summary
This summary is machine-generated.

Uterine fibroids, particularly submucous types, can impact fertility and increase spontaneous abortion (SAB) risks. Surgical treatment like myomectomy may offer benefits, but more research is needed for definitive conclusions.

Related Experiment Videos

Last Updated: Jun 13, 2026

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
05:46

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation

Published on: January 17, 2019

Area of Science:

  • Reproductive Medicine
  • Gynecologic Oncology

Background:

  • Uterine fibroids are common in women with reproductive issues like infertility and spontaneous abortion (SAB).
  • The causal link between fibroids and reproductive outcomes, and the efficacy of surgical treatment, require further clarification.

Purpose of the Study:

  • To evaluate the impact of uterine fibroids on fertility, spontaneous abortion rates, and obstetric complications.
  • To assess the potential benefits of myomectomy in improving reproductive outcomes.

Main Methods:

  • Review and synthesis of existing data on uterine fibroids and reproductive outcomes.
  • Analysis of the effects of different fibroid types (submucous, intramural, subserosal) on fertility and pregnancy.

Main Results:

  • Submucous fibroids are linked to decreased fertility and increased SAB rates; myomectomy may be beneficial.
  • Intramural fibroids may affect fertility and increase miscarriage risk, with unclear benefits of myomectomy.
  • Subserosal fibroids do not appear to impair fertility but may increase SAB rates.
  • Fibroids are associated with increased risks of various obstetric complications, including cesarean delivery and preterm labor.

Conclusions:

  • The precise impact of fibroids on reproductive health is complex and influenced by fibroid type and location.
  • Evidence suggests submucous myomectomy can improve fertility and reduce SAB, while benefits for other types are less certain.
  • High-quality research is essential to confirm these findings and guide clinical management of uterine fibroids in women with reproductive disorders.