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Updated: Jun 13, 2026

Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo
08:32

Detection of the pH-dependent Activity of Escherichia coli Chaperone HdeB In Vitro and In Vivo

Published on: October 23, 2016

Physicochemical determinants of chaperone requirements

Gian Gaetano Tartaglia1, Christopher M Dobson, F Ulrich Hartl

  • 1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.

Journal of Molecular Biology
|April 27, 2010
PubMed
Summary

Scientists found that protein abundance and solubility predict the need for the GroEL chaperonin in E. coli. Protein sequences alone can also predict this need, highlighting sequence properties in cellular quality control.

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