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Electrically evoked auditory brainstem responses in children with sequential bilateral cochlear implants.

Marloes Sparreboom¹, Andy J Beynon, Ad F M Snik

¹Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Otorhinolaryngology, Head and Neck Surgery, Nijmegen, The Netherlands. m.sparreboom@kno.umcn.nl

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [And] European Academy of Otology and Neurotology

|April 27, 2010

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Sequential bilateral cochlear implantation (CI) shows auditory brainstem maturation, but the second implant (CI2) side may lag behind the first (CI1). Age at CI2 does not significantly impact latency differences over time.

Area of Science:

Neuroscience
Audiology
Pediatric Medicine

Background:

Sequential bilateral cochlear implantation (CI) is a common treatment for prelingual deafness.
Understanding auditory brainstem maturation after CI is crucial for optimizing auditory development.
The impact of the age at second CI (CI2) on brainstem maturation remains an area of investigation.

Purpose of the Study:

To investigate the effect of sequential bilateral cochlear implantation on auditory brainstem maturation.
To determine the influence of the age at receiving the second cochlear implant (CI2) on auditory brainstem development.

Main Methods:

A prospective cohort study was conducted at a tertiary academic referral center.
Thirty prelingually deaf children received sequential bilateral cochlear implantation (CI1 at 1.8 years, CI2 at 5.3 years).

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Electrically evoked auditory brainstem responses (eABRs) were measured intraoperatively and at 6, 12, and 24 months postoperatively.

Main Results:

Wave V latency was initially prolonged on the CI2 side compared to CI1, but this difference became non-significant after 12-24 months.
Interwave interval III-V latencies remained significantly prolonged on the CI2 side.
Age at CI2 did not correlate with individual latency differences across all measured waveforms.

Conclusions:

Auditory brainstem maturation occurs after sequential bilateral cochlear implantation, even after a period of unilateral deafness.
The CI2 side shows some persistent abnormalities compared to the CI1 side, suggesting incomplete catch-up.
While interaural latencies decrease over time, longer follow-up may reveal full maturation of the CI2 side.