Related Experiment Video
Updated: Jun 13, 2026
06:59
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
[Ambiguous swelling of the earlobe].
1Hals-Nasen-Ohrenklinik und Poliklinik, Klinikum rechts der Isar der technischen Universität München, Ismaninger Str. 22, 81675 München. a.knopf@lrz.tum.de
HNO
|April 27, 2010
Summary
Cutaneous lymphoid hyperplasia, a rare skin manifestation, was diagnosed in a child with a persistent earlobe swelling. This condition indicated stage II Lyme borreliosis (Lyme disease) and was successfully treated with antibiotics.
Area of Science:
- Dermatology
- Infectious Diseases
- Pediatrics
Background:
- Lyme borreliosis is a tick-borne illness with diverse clinical presentations.
- Cutaneous manifestations are common but can be non-specific.
- Early diagnosis and treatment are crucial for managing Lyme borreliosis.
Observation:
- A 2-year-old girl presented with a 6-month history of a reddish earlobe swelling.
- Initial clinical presentation was unspecific, prompting a biopsy.
- Histological examination revealed a lymphocyte-rich infiltration with lymph follicles.
Findings:
- The histological findings were consistent with cutaneous lymphoid hyperplasia.
- Cutaneous lymphoid hyperplasia is a rare but recognized manifestation of stage II Lyme borreliosis.
- The patient's condition was linked to Lyme borreliosis infection.
Implications:
- This case highlights the importance of considering Lyme borreliosis in pediatric patients with persistent skin lesions, even with atypical presentations.
- Cutaneous lymphoid hyperplasia can serve as an indicator of disseminated Lyme borreliosis.
- Prompt antibiotic treatment led to successful resolution of the infection and skin manifestation.
Related Concept Videos
01:16Anatomy of the Ear
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
01:11The Auditory Ossicles
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
01:30Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
01:23Cirrhosis I: Introduction
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
01:25Cardiovascular System Abnormal Findings II: Auscultation
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
01:19Ascites
DefinitionAscites is the buildup of fluid inside the peritoneal cavity. It occurs when fluid moves out of the vascular system faster than the peritoneal lymphatics can remove it. This fluid shift is most commonly seen in liver cirrhosis but can also appear in several other systemic disorders.EtiologyCirrhosis remains the leading cause of ascites. Other conditions that can contribute include:Heart failureConstrictive pericarditisAbdominal cancersNephrotic syndromeSevere protein–calorie...