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Related Concept Videos

Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

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Related Experiment Video

Updated: Jun 13, 2026

Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis
06:14

Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis

Published on: January 12, 2024

New treatments for gout.

Janet B Mapa1, Michael H Pillinger

  • 1NYU Hospital for Joint Diseases, Division of Rheumatology, 301 East 17th Street, Room 1410, New York, NY 10003, USA.

Current Opinion in Investigational Drugs (London, England : 2000)
|April 27, 2010
PubMed
Summary

New gout treatments are needed due to comorbidities limiting current therapies. This review covers emerging drugs targeting urate levels and inflammation for gouty arthritis management.

Area of Science:

  • Rheumatology
  • Pharmacology

Background:

  • Gouty arthritis treatments have seen minimal advancement since the 1960s.
  • Existing therapies for acute and chronic gout are often contraindicated in patients with common comorbidities like diabetes and renal insufficiency.
  • There is a significant unmet need for novel therapeutic strategies in gout management.

Purpose of the Study:

  • To review recent advancements in gout therapeutics.
  • To discuss novel drugs aimed at reducing urate levels.
  • To explore new anti-inflammatory agents for gouty arthritis.

Main Methods:

  • Literature review of recent therapeutic developments in gout.
  • Analysis of drugs targeting urate reduction.
  • Examination of anti-inflammatory strategies for gout.

Related Experiment Videos

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Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis
06:14

Tuina Intervention in Sodium Monoiodoacetate Injection-Induced Rat Model of Knee Osteoarthritis

Published on: January 12, 2024

Main Results:

  • Several new therapeutic strategies for gout are emerging.
  • These include drugs designed to lower serum urate levels.
  • Novel anti-inflammatory agents for acute and chronic gout are also under development.

Conclusions:

  • Recent advances offer promising new avenues for gout treatment.
  • Emerging therapies address limitations of current treatments, particularly in patients with comorbidities.
  • These novel therapeutics are in various stages of development and regulatory evaluation.