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[Septic shock in intensive care]
Anders Perner1, Sarah Carlsen, Klaus Marcussen
1Intensiv Terapiklinik 4131, Rigshospitalet, DK-2100 København Ø, Denmark. anders.perner@rh.regionh.dk
Ugeskrift for Laeger
|April 29, 2010
Summary
This study assessed septic shock patients in Danish intensive care units (ICUs), finding high mortality rates similar to international benchmarks. Treatment protocols were consistent across diverse patient admissions.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Epidemiology
Background:
- Septic shock carries a high mortality rate (33-42% at 30 days).
- Limited data exists on septic shock patient characteristics and outcomes in Danish intensive care units (ICUs).
Purpose of the Study:
- To characterize patients with septic shock in Danish ICUs.
- To assess the outcomes, including 30- and 90-day mortality, for these patients.
Main Methods:
- A prospective cohort study was conducted over 3 months.
- 132 patients with septic shock across six Danish ICUs were included.
- Data on demographics, infection focus, and initial treatment were collected, along with mortality at 30 and 90 days.
Main Results:
- The median patient age was 64 years, with diverse admission sources.
- Abdominal (47) and pulmonary (45) infections were the most common causes.
- 30-day mortality was 33% and 90-day mortality was 41%, with higher rates for abdominal infections (42% and 55%).
Conclusions:
- Septic shock patients in Danish ICUs present with varied origins and infection types but receive uniform treatment.
- Mortality rates are high but comparable to leading international outcomes.
- Further research may explore specific interventions to improve outcomes.
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