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Chronic kidney disease, diabetes, and hypertension: what's in a name?
Andrew S Levey1, Brad C Astor, Lesley A Stevens
1Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA. alevey@tuftsmedicalcenter.org
Insights
Chronic kidney disease (CKD) affects over 11% of US adults, often linked to diabetes and hypertension. This study examines CKD causes and the rationale for its current name.
Area of Science:
- Nephrology
- Epidemiology
- Vascular Medicine
Background:
- Chronic kidney disease (CKD) impacts 11.6% of US adults.
- CKD is frequently comorbid with diabetes and hypertension.
- Vascular disease is a suspected primary cause in many CKD cases.
Purpose of the Study:
- To present data on the prevalence of diabetes and hypertension in CKD patients.
- To analyze these comorbidities based on albumin-to-creatinine ratio and eGFR.
- To review the justification for the current nomenclature of CKD.
Main Methods:
- Data analysis of diabetes and hypertension frequency in CKD.
- Stratification by albumin-to-creatinine ratio.
- Stratification by estimated glomerular filtration rate (eGFR).
Main Results:
- Prevalence data for diabetes, hypertension, or both in relation to CKD markers.
- Analysis of comorbidity frequency across different eGFR and albuminuria levels.
- Discussion on the etiological implications for CKD classification.
Conclusions:
- Diabetes and hypertension are highly prevalent in CKD patients.
- Understanding comorbidity patterns is crucial for CKD management.
- The current name for chronic kidney disease is reviewed in light of its common causes.
Abstract:
Chronic kidney disease, as defined by albuminuria or decreased estimated glomerular filtration rate (eGFR), affects 11.6% of the adult population in the United States. CKD frequently occurs in association with diabetes and hypertension, suggesting that vascular disease is a likely cause in many people. We provide data on the frequency of diabetes, hypertension, or both, according to albumin-to-creatinine ratio and eGFR, and review the rationale for retaining the current name.
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