Chronic kidney disease, diabetes, and hypertension: what's in a name?

Andrew S Levey1, Brad C Astor, Lesley A Stevens

  • 1Division of Nephrology, Tufts New England Medical Center, Boston, Massachusetts 02111, USA. alevey@tuftsmedicalcenter.org

Kidney International
|April 30, 2010
PubMed

Insights

Chronic kidney disease (CKD) affects over 11% of US adults, often linked to diabetes and hypertension. This study examines CKD causes and the rationale for its current name.

Area of Science:

  • Nephrology
  • Epidemiology
  • Vascular Medicine

Background:

  • Chronic kidney disease (CKD) impacts 11.6% of US adults.
  • CKD is frequently comorbid with diabetes and hypertension.
  • Vascular disease is a suspected primary cause in many CKD cases.

Purpose of the Study:

  • To present data on the prevalence of diabetes and hypertension in CKD patients.
  • To analyze these comorbidities based on albumin-to-creatinine ratio and eGFR.
  • To review the justification for the current nomenclature of CKD.

Main Methods:

  • Data analysis of diabetes and hypertension frequency in CKD.
  • Stratification by albumin-to-creatinine ratio.
  • Stratification by estimated glomerular filtration rate (eGFR).

Main Results:

  • Prevalence data for diabetes, hypertension, or both in relation to CKD markers.
  • Analysis of comorbidity frequency across different eGFR and albuminuria levels.
  • Discussion on the etiological implications for CKD classification.

Conclusions:

  • Diabetes and hypertension are highly prevalent in CKD patients.
  • Understanding comorbidity patterns is crucial for CKD management.
  • The current name for chronic kidney disease is reviewed in light of its common causes.

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