Related Experiment Video
Updated: Jun 13, 2026
14:14
Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
Published on: April 16, 2017
[A study of skin deformation by optical coherent microscopy]
Biofizika
|May 1, 2010
Summary
Rat skin deformation during cooling is caused by collagen fiber bundles contracting, not by piloerector or vasoconstrictor muscles. Optical coherent microscopy revealed this key insight into skin
Area of Science:
- Biophysics
- Dermatology
- Tissue Mechanics
Context:
- Investigating the physiological responses of skin to thermal stimuli.
- Understanding the role of nerve fiber stimulation in skin deformation.
- Utilizing advanced imaging techniques like optical coherent microscopy for in vivo studies.
Purpose:
- To elucidate the primary mechanism behind rat skin deformation upon cooling.
- To differentiate the contributions of collagen fibers versus smooth muscles in this response.
- To analyze the effects of nerve fiber stimulation on skin tissue.
Summary:
- Optical coherent microscopy was employed to study rat skin deformation.
- Cooling-induced deformation was attributed to collagen fiber bundle contraction.
- Smooth muscles of piloerectors and vasoconstrictors were found not to be the primary cause.
Impact:
- Provides a refined understanding of skin's biomechanical response to cold.
- Highlights the significant role of collagenous structures in skin elasticity and contraction.
- Offers insights for potential applications in dermatology and biomaterials.
Related Concept Videos
01:12Temperature Dependent Deformation
In a nonhomogeneous rod made up of steel and brass, restrained at both ends and subjected to a temperature change, several steps are involved in calculating the stress and compressive load. Due to the problem's static indeterminacy, one end support is disconnected, allowing the rod to experience the temperature change freely. Next, an unknown force is applied at the free end, triggering deformations in the rod's steel and brass portions. These deformations are then calculated and added together...
01:11Deformation of Member under Multiple Loadings
When a rod is made of different materials or has various cross-sections, it must be divided into parts that meet the necessary conditions for determining the deformation. These parts are each characterized by their internal force, cross-sectional area, length, and modulus of elasticity. These parameters are then used to compute the deformation of the entire rod.
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
In the case of a member with a variable cross-section, the strain is not constant but depends on the position. The deformation of an...
01:18Imaging Biological Samples with Optical Microscopy
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...