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Updated: Jun 13, 2026

Electric Cell-Substrate Sensing for Real-Time Evaluation of Metal-Organic Framework Toxicological Profiles
Published on: May 26, 2023
[Report on the influence of some materials on the proliferation of cells.]
V Pesáková1, S Beznoska, O Cech
1Revmatologický ústav, Praha.
Abstract:
The authors have examined the biocompatibility of four materials used for the production of implants with the proliferation of cells. This applies mainly to Ti-6 AI-4 V, Ti- 5AI-2,5 Fe, AKV-Ultra 2 alloys and also to the carbon filament connected by polyamide. In their study the authors used diploid clone -human embryonal fibroblasts LEP and heteroploid lines - Vero cells. It has been found out that neither of the materials tested is of a toxic nature, however, under certain conditions there occurs the reduction of proliferation abilities of cells most probably due to the influence of agents which have passed to the cultivation medium. Key words: fibroblasts, DNA, implant materials: (C+polyamide, steel AKV-Ultra 2, Ti-6 AI-4 V, Ti-5 AI-2,5 Fe).

