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DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Ultrasensitive and selective DNA detection based on nicking endonuclease assisted signal amplification and its
Sai Bi1, Jilei Zhang, Shusheng Zhang
1Key Laboratory of Eco-chemical Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Chemical Communications (Cambridge, England)
|May 1, 2010
Abstract:
By significantly circumventing the typical problem of high background induced by excess hemin itself, an ultrasensitive DNA amplified detection method is developed based on nicking endonuclease (NEase) assisted strand scission cycle, which is further successfully applied in cancer cell detection.