[Linear accelerator-based stereotactic radiotherapy in combined treatment of skull base chordomas]

Short-term results of postoperative stereotactic linear accelerator-based radiation treatment of 18 patients with cranial base chordomas are analyzed. Total dose was 70 Gy or more. Control of tumor growth confirmed by CT and/or MRI was achieved in 15 cases (83%). Only 1 patient had complication--visual deficit which resolved after 3 months. Control group consisted of 73 patients treated only surgically. 38% of cases in this group were recurrence-free. The study has demonstrated effectiveness of radiotherapy of skull base chordomas.