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Fibrous hamartoma of infancy. Case report
Leticia del Carmen Baena-Ocampo1, Luis Miguel Linares-González, Norma Marín-Arriaga
1Servicio de Anatomía Patológica, Instituto Nacional de Rehabilitación, México, DF, Mexico. lcbaena@yahoo.com
Insights
Fibrous hamartoma of infancy (FHI) is a rare benign soft tissue tumor typically seen in infants. This case highlights FHI presenting as a foot tumor in a 6-month-old, emphasizing its characteristic morphology and treatment.
Area of Science:
- Pediatric Pathology
- Soft Tissue Tumors
- Dermatopathology
Background:
- Fibrous hamartoma of infancy (FHI) is an uncommon benign soft tissue proliferation, predominantly affecting infants under one year old.
- FHI typically presents as a subcutaneous lesion with a distinct triphasic organoid growth pattern on histopathology.
Observation:
- A case report of a 6-month-old male infant with a medial plantar foot tumor is presented.
- The lesion presented as a completely withered mass.
- Histopathological examination confirmed the diagnosis of fibrous hamartoma of infancy.
Findings:
- Fibrous hamartoma of infancy predominantly affects males and can occur at any anatomical site.
- While lower limb involvement is noted in 5-10% of cases, foot localization is rare.
- Characteristic morphological patterns are key, but differentiation from other fibroadipose lesions is crucial in small biopsies.
Implications:
- Accurate histopathological diagnosis is vital for appropriate management of fibrous hamartoma of infancy.
- Complete surgical resection with clear margins is the recommended treatment.
- This approach ensures a favorable prognosis for affected patients.
Background:
Fibrous hamartoma of infancy (FHI) is an infrequent benign proliferation of the soft tissues. Ninety one percent of cases occur during the first year of life. FHI is characterized as a subcutaneous lesion with characteristic morphology with a triphasic organoid growth pattern.
Clinical Case:
We present the case of a 6-month-old male infant with a tumor in the medial plantar region of the left foot, which was completely withered. Histopathological study reported a fibrous hamartoma of infancy.
Conclusions:
Fibrous hamartoma of infancy most frequently affects males. It may be localized at any anatomic site, although 5-10% of cases affect the lower limbs. Few cases are reported in the foot. This is a lesion with a characteristic morphological pattern; however, in small biopsies, its differential diagnosis is important with other fibroadipose lesions for appropriate treatment. Ample surgical resection with lesion-free borders confers a good prognosis for these patients.