Nuts, metabolic syndrome and diabetes
Cyril W C Kendall1, Andrea R Josse, Amin Esfahani
1Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada M5S 3E2. cyril.kendall@utoronto.ca
The British Journal of Nutrition
|May 6, 2010
Summary
Nuts can improve blood lipids and reduce heart disease risk. While not directly improving long-term blood sugar control, they help manage blood glucose spikes when eaten with carbohydrates.
Area of Science:
- Nutritional Science
- Cardiovascular Health
- Metabolic Health
Background:
- Nuts are known to improve blood lipid profiles and reduce coronary heart disease (CHD) risk.
- Recent interest focuses on nuts' benefits for metabolic syndrome and diabetes prevention/control.
- Cohort studies link nut consumption to reduced risk of diabetes and cardiovascular disease (CVD).
Purpose of the Study:
- To assess the effects of nuts on diabetes control, particularly glycaemic control.
- To evaluate the impact of nuts on postprandial glycaemia.
- To determine if nuts warrant inclusion in diets for individuals with diabetes and metabolic syndrome.
Main Methods:
- Review of existing cohort studies and randomised controlled trials (RCTs) on nut consumption and health outcomes.
- Analysis of acute feeding studies examining the effects of nuts on postprandial blood glucose levels.
- Evaluation of the nutritional profile of nuts, including fatty acids, protein, fiber, vitamins, and minerals.
Main Results:
- RCTs show nuts improve blood lipids but not long-term glycaemic control in diabetes.
- Acute studies indicate nuts have minimal impact on blood glucose alone but reduce postprandial glycaemic response when consumed with high-glycaemic index carbohydrates.
- Nuts possess a healthy nutritional profile beneficial for overall diet quality.
Conclusions:
- While long-term glycaemic control benefits require further research, early data suggest nuts are beneficial for individuals with diabetes and metabolic syndrome.
- Nuts' potential to reduce CHD risk supports their inclusion in dietary recommendations for these populations.
- Incorporating nuts may improve overall nutritional quality and aid in managing metabolic health conditions.
More Related Videos
Related Concept Videos
Type II Diabetes I: Introduction
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Type II Diabetes II: Pathophysiology
PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Pathophysiology of Diabetes
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Diabetes: Symptoms, Diagnosis, and Complications
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Diabetes Mellitus: Introduction
Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...


