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Updated: Jun 13, 2026

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Herpes simplex virus pneumonia: high-resolution CT findings
1Department of Radiology, Chung-Ang University Medical Center, Chung-Ang University College of Medicine, Seoul 156-755, South Korea.
High-resolution computed tomography (HRCT) reveals distinct patterns in herpes simplex virus (HSV) pneumonia, including ground-glass attenuation and consolidations. These findings aid in diagnosing HSV pneumonia in both immunocompromised and immunocompetent patients.
Area of Science:
- Radiology
- Pulmonology
- Infectious Diseases
Background:
- Herpes simplex virus (HSV) pneumonia is a rare but serious lower respiratory tract infection.
- Accurate diagnosis is crucial for timely and effective treatment.
Purpose of the Study:
- To evaluate the high-resolution computed tomographic (HRCT) findings in adult patients with herpes simplex virus (HSV) pneumonia.
- To identify characteristic HRCT patterns associated with HSV pneumonia.
Main Methods:
- Retrospective analysis of HRCT images from five adult patients diagnosed with HSV pneumonia.
- Correlation of HRCT findings with histopathological data (intranuclear inclusion bodies, immunohistochemical staining) when available.
- Assessment of parenchymal abnormalities including ground-glass attenuation, consolidation, nodules, and septal thickening.
Main Results:
- Three predominant HRCT patterns were identified: diffuse/multifocal ground-glass attenuation, multifocal peribronchial consolidations, or a mixed pattern.
- Ground-glass attenuation on HRCT corresponded to diffuse alveolar damage in one case.
- No significant HRCT finding differences were observed between immunocompromised and immunocompetent patients.
Conclusions:
- HRCT can reveal characteristic patterns in HSV pneumonia, including ground-glass attenuation and consolidations.
- HSV pneumonia should be considered in the differential diagnosis of acute lower respiratory infections with these HRCT findings, regardless of immune status.
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