Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Repeated plasma volume determination with the Evans Blue dye dilution technique: the method and a computer program.

N Foldager1, C G Blomqvist

  • 1Danish Aerospace Medical Centre of Research, National Hospital, Copenhagen.

Computers in Biology and Medicine
|January 1, 1991
PubMed
Summary

This study introduces a reliable Evans Blue dye method for measuring plasma and blood volume. A new Pascal program accurately calculates these volumes, ensuring precise and reproducible results in physiological research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Human baroreflex rhythms persist during handgrip and muscle ischaemia.

Acta physiologica (Oxford, England)·2013
Same author

Simultaneous determination of the accuracy and precision of closed-circuit cardiac output rebreathing techniques.

Journal of applied physiology (Bethesda, Md. : 1985)·2007
Same author

A 30-year follow-up of the Dallas Bedrest and Training Study: I. Effect of age on the cardiovascular response to exercise.

Circulation·2001
Same author

A 30-year follow-up of the Dallas Bedrest and Training Study: II. Effect of age on cardiovascular adaptation to exercise training.

Circulation·2001
Same author

General recommendations.

Brain research. Brain research reviews·2001
Same author

Chest volume and shape and intrapleural pressure in microgravity--reply [letter ; comment].

Journal of applied physiology (Bethesda, Md. : 1985)·2001

Area of Science:

  • Physiology
  • Biomedical Engineering
  • Computational Biology

Background:

  • Accurate measurement of plasma and blood volume is crucial for physiological research.
  • Existing methods may lack reliability or require complex calculations.

Purpose of the Study:

  • To describe a dependable multiple sample Evans Blue dye dilution technique.
  • To introduce a Pascal program for automated plasma and blood volume computation.

Main Methods:

  • Utilized a multiple sample Evans Blue dye dilution technique.
  • Developed a Pascal program for data correction, curve fitting, and volume calculation.
  • Included menu-driven facilities for data management and graphical display.

Main Results:

Related Experiment Videos

  • The developed technique and program provide reliable plasma volume measurements.
  • Three plasma volume determinations in six subjects showed no statistically significant differences (means: 3239 +/- 96 ml, 3189 +/- 81 ml, 3187 +/- 102 ml).

Conclusions:

  • The Evans Blue dye dilution technique combined with the Pascal program offers a robust method for determining plasma and blood volume.
  • The automated system ensures accuracy and ease of use in physiological studies.