Related Experiment Video
Updated: Jun 13, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
[Late gadolinium enhancement in the diagnostics of ischemic heart disease: technical principles, contrast
K U Bauner1, A Biffar, M Greif
1Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Marchioninistr. 15, 81377, München, Deutschland. Kerstin.Bauner@med.uni-muenchen.de
Insights
The novel "dark blood" technique may improve detection of small subendocardial infarctions. However, the standard inversion recovery gradient echo (IR GRE) sequence remains superior for visualizing infarcts within the myocardium.
Area of Science:
- Cardiovascular Imaging
- Magnetic Resonance Imaging (MRI)
Context:
- Myocardial infarction (MI) detection is crucial for patient outcomes.
- Standard MRI sequences like inversion recovery gradient echo (IR GRE) are used for MI visualization.
- Novel techniques are being explored to improve diagnostic accuracy.
Purpose:
- To evaluate a "dark blood" MRI technique for myocardial infarction visualization.
- To compare the performance of the "dark blood" technique against the standard IR GRE sequence.
Summary:
- The study compared a "dark blood" sequence with IR GRE in 9 patients post-contrast administration.
- Contrast-to-noise ratios (CNR) were calculated to assess image quality.
- The "dark blood" technique showed a higher CNR for infarct-to-left ventricular cavity (inf-lvc) but a lower CNR for infarct-to-myocardium (inf-myo).
Impact:
- The "dark blood" technique may enhance the detection of small subendocardial infarctions.
- The standard IR GRE sequence is currently superior for delineating infarcts within the myocardium.
- The "dark blood" technique does not replace the standard IR GRE sequence for comprehensive MI assessment.
Background:
The purpose of the study was to explore a "dark blood" technique and to compare it with a standard inversion recovery gradient echo (IR GRE) sequence in the visualization of myocardial infarction.
Patients And Methods:
A total of 9 patients were examined with standard IR GRE and a "dark blood" sequence 15 mins after contrast medium application (0.2 mmol/kg body weight gadobenate dimeglumine). Contrast-to-noise ratios (CNR) were calculated for each sequence.
Results:
The CNR(inf-lvc) was significantly higher in the "dark blood" technique compared to the IR GRE sequence, while the CNR(inf-myo) was significantly lower.
Conclusions:
Small subendocardial infarctions may be easier to detect with the "dark blood" technique. However, the standard IR GRE sequence is superior in the demarcation of infarctions in relation to the myocardium and cannot be replaced by the "dark blood" technique.
Related Concept Videos
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome III: Diagnostic Studies
Cardiac Catheterization I: Pre-Procedure Overview
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Magnetic Resonance Imaging
