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Updated: Jun 13, 2026

Assembly and Purification of Prototype Foamy Virus Intasomes
Published on: March 19, 2018
Molecular biology of foamy viruses
1Institut für Virologie und Immunbiologie, University of Würzburg, Versbacher Str. 7, Würzburg, Germany. virologie@vim.uni-wuerzburg.de
Abstract:
One of the most fascinating areas in retrovirology is the study of foamy viruses (FVs), because these viruses appear to do everything that is common to all other retroviruses differently. FVs have found a completely new way to propagate their genome. And they do this extremely successfully because most of wild non-human primates, felines, bovines, equines, and small ruminants are likely to be non-pathogenically infected. The success of FVs can also be viewed from a different angle, since they replicate very conservatively and do not need to shape their genotypic and phenotypic makeup every now and then. The elucidation of the underlying basic mechanisms of the FV replication strategy is the topic of this review.
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