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Updated: Jun 13, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
Published on: December 9, 2016
[Rare localization of sarcoma in an adolescent: thoracic Ewing sarcoma]
Leila El Fekih1, Hela Hassene, Hajer Abdelghaffar
1Service de Pneumologie ibn nafis, Hopital Abderrhman Mamini de l'Ariana.
Ewing sarcoma, a primitive neuroectodermal tumor, can rarely occur in the thorax. This case highlights the importance of considering thoracic Ewing sarcoma in the differential diagnosis of mediastinal masses.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Diagnostic Imaging
Background:
- Ewing sarcoma is a primitive neuroectodermal tumor, predominantly affecting children and adolescents.
- While commonly found in long bones and the pelvis, it can also arise from the rib cage.
Observation:
- A 15-year-old female presented with scapular pain and weight loss, indicative of a potential thoracic malignancy.
- Imaging revealed a mediastinal mass with vertebral metastasis, leading to rapid clinical deterioration and spinal cord compression.
Findings:
- Histopathological and immunohistochemical analysis confirmed the diagnosis of pediatric Ewing sarcoma.
- The patient received radiotherapy, laminectomy, and chemotherapy, showing significant motor recovery.
Implications:
- This case underscores that thoracic localization of Ewing sarcoma, though uncommon, should be considered in the evaluation of mediastinal masses.
- Early and accurate diagnosis is crucial for timely intervention and improved patient outcomes in rare pediatric malignancies.
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