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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

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Related Experiment Video

Updated: Jun 13, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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Prostate cancer diagnosis.

Peter A Humphrey1, Gerald L Andriole

  • 1Washington University School of Medicine in St. Louis, USA. humphrey@path.wustl.edu

Missouri Medicine
|May 8, 2010
PubMed
Summary

Prostate cancer, a common malignancy in Missouri, is often diagnosed via elevated prostate specific antigen (PSA) or rectal exam findings. This review focuses on diagnosing localized prostate cancer using needle biopsy methods.

Area of Science:

  • Oncology
  • Urology
  • Pathology

Background:

  • Prostate cancer is the fourth most common malignancy in Missouri.
  • Clinical suspicion arises from elevated prostate specific antigen (PSA) and/or digital rectal examination abnormalities.
  • Symptoms often indicate advanced disease stages.

Purpose of the Study:

  • To review clinical and pathological diagnostic approaches for prostate cancer.
  • To focus on the diagnosis of clinically localized prostate cancer.
  • To emphasize the role of needle biopsy in diagnosis.

Main Methods:

  • Review of clinical diagnostic criteria for prostate cancer.
  • Examination of pathological diagnostic techniques for prostate cancer.
  • Focus on histopathologic evaluation of needle biopsy specimens.

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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

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A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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Main Results:

  • Elevated PSA and digital rectal exam findings suggest prostate cancer.
  • Needle biopsy provides definitive histopathologic diagnosis.
  • Clinical presentation often correlates with disease stage.

Conclusions:

  • Accurate diagnosis of prostate cancer relies on integrated clinical and pathological assessments.
  • Needle biopsy is the gold standard for diagnosing localized prostate cancer.
  • Early detection strategies are crucial for managing prostate cancer effectively.