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Published on: January 15, 2022
[Arteriosclerosis obliterans (ASO)]
Megumi Koshikawa1, Uichi Ikeda
1Department of Cardiovascular Medicine, Shinshu University.
Insights
Arteriosclerosis Obliterans (ASO) treatment aims to reduce cardiovascular events and prevent limb loss by managing risk factors. Key strategies include lifestyle changes, medication, and surgical interventions for improved patient outcomes.
Area of Science:
- Vascular Medicine
- Cardiovascular Disease
- Peripheral Artery Disease
Context:
- Arteriosclerosis Obliterans (ASO) significantly impacts patient quality of life and physical function.
- ASO patients face elevated risks of myocardial infarction and stroke.
- Limb amputation is a severe complication of untreated ASO.
Purpose:
- To outline comprehensive treatment goals for Arteriosclerosis Obliterans.
- To emphasize aggressive management of atherosclerotic risk factors.
- To highlight strategies for symptom improvement and prevention of severe outcomes.
Summary:
- ASO treatment focuses on reducing future cardiovascular events and claudication symptoms.
- Management involves risk factor modification, smoking cessation, exercise, and pharmacologic therapy.
- Interventional options include angioplasty, stenting, bypass surgery, and therapeutic angiogenesis.
Impact:
- Effective ASO management can prevent limb amputation and reduce cardiovascular mortality.
- Improved treatment strategies enhance patient quality of life and physical function.
- Integrated care addressing both peripheral and systemic atherosclerosis is crucial.
Abstract:
The goal of treatment in arteriosclerosis obliterans (ASO) is to aggressively treat atherosclerotic risk factors to reduce future cardiovascular events as well as to improve symptoms of claudication and prevent limb amputation. Patients with ASO have an increased risk of cardiovascular events such as myocardial infarction and stroke in addition to significant impairment in their quality of life and physical function. Strategies for management of ASO include conservative treatment with risk factor modification, smoking cessation, exercise, pharmacologic therapy, balloon angioplasty and stenting of vessels, or bypass surgery, and therapeutic angiogenesis. In addition, the prevention and treatment for cardiovascular events such as myocardial infarction and stroke are important, too.
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