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Lymphangitis after tuberculin test.

D Bouros1, M Niotis, V Blatsios

  • 1Pulmonary Dept., Army General Hospital, Athens, Greece.

The European Respiratory Journal
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

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A rare severe reaction occurred after a tuberculosis skin test. Extensive redness, swelling, and lymph node inflammation developed in one soldier after purified protein derivative (PPD) testing.

Area of Science:

  • Immunology
  • Infectious Diseases
  • Dermatology

Background:

  • The Mantoux test, using purified protein derivative (PPD), is a standard method for tuberculosis screening.
  • Tuberculin hypersensitivity reactions are generally localized and mild.

Observation:

  • A 28-year-old male soldier experienced significant local and regional adverse effects following a Mantoux test.
  • The reaction included extensive erythema (redness), induration (swelling), and proximal lymphangitis (inflammation of lymph vessels).

Findings:

  • This case represents an exceptionally rare and severe localized hypersensitivity reaction to the Mantoux test.
  • The incidence was 1 in approximately 500,000 subjects over a 10-year period in the Greek Army, highlighting its rarity.

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Implications:

  • While rare, severe reactions to PPD testing necessitate awareness and prompt medical evaluation.
  • Understanding the spectrum of potential adverse events is crucial for patient safety in tuberculosis screening programs.