Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2011
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2011
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2010
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2010
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2010
Same author

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacologyยท2010
Same journal

[Proceedings of the XVIII TASPE Seminar, Granada, Spain, 4-5 February 2010].

Methods and findings in experimental and clinical pharmacologyยท2011
Same journal

[Treatment algorithm for gastrointestinal graft-versus-host disease].

Methods and findings in experimental and clinical pharmacologyยท2011
Same journal

[Treatment of chronic graft-versus-host disease with protein tyrosine kinase inhibitors].

Methods and findings in experimental and clinical pharmacologyยท2011
Same journal

[Classification of chronic graft-versus-host disease].

Methods and findings in experimental and clinical pharmacologyยท2011
Same journal

[Pegfilgrastim in hematopoietic stem cell transplantation].

Methods and findings in experimental and clinical pharmacologyยท2011
Same journal

[Allogeneic transplantation in multiple myeloma patients: results and recommendations in February 2010].

Methods and findings in experimental and clinical pharmacologyยท2011
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

Gateways to clinical trials.

A Tomillero1, M A Moral

  • 1Thomson Reuters, Barcelona, Spain. scientific.prousjournals@thomsonreuters.com

Methods and Findings in Experimental and Clinical Pharmacology
|May 8, 2010
PubMed
Summary
This summary is machine-generated.

This study provides a comprehensive list of pharmaceutical agents, including antivirals, anticancer drugs, and cardiovascular medications, for researchers and clinicians. It serves as a valuable resource for drug discovery and therapeutic development.

More Related Videos

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

Related Experiment Videos

Last Updated: Jun 13, 2026

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
04:53

A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

Published on: September 20, 2019

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

Area of Science:

  • Pharmacology and Drug Discovery
  • Medicinal Chemistry
  • Clinical Therapeutics

Context:

  • The pharmaceutical industry continuously develops novel therapeutic agents.
  • A wide array of drugs target diverse disease areas, including viral infections, cancer, and cardiovascular diseases.
  • Understanding the nomenclature and applications of these agents is crucial for researchers and clinicians.

Purpose:

  • To compile and present a broad spectrum of pharmaceutical compounds.
  • To serve as a reference for drugs currently in development or clinical use.
  • To highlight the diversity of chemical entities and their therapeutic targets.

Summary:

  • The abstract lists numerous pharmaceutical agents, encompassing antivirals (e.g., Adefovir dipivoxil, Entecavir), anticancer drugs (e.g., Clofarabine, Dasatinib), cardiovascular agents (e.g., Aliskiren fumarate, Rosuvastatin calcium), and others.
  • Included are biologics like Alemtuzumab and Golimumab, as well as drug-eluting stents.
  • The list represents a snapshot of pharmaceutical innovation across various medical fields.

Impact:

  • Facilitates quick identification of drug names and their potential therapeutic classes.
  • Aids researchers in drug discovery and development by providing a comprehensive overview.
  • Supports clinicians in staying updated with the evolving pharmaceutical landscape.