Related Experiment Video
Updated: Jun 13, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Oral mucosal lesions in children from 0 to 12 years old: ten years' experience
Alessandra Majorana1, Elena Bardellini, Pierangela Flocchini
1Dental Institute, University of Brescia, Brescia, Italy.
Insights
Oral mucosal lesions affect nearly 30% of children, with oral candidiasis being the most common. Underlying medical conditions increase the risk of these common childhood oral lesions.
Area of Science:
- Pediatric Dentistry
- Oral Medicine
- Epidemiology
Background:
- The prevalence of oral mucosal lesions in pediatric populations is not well-established.
- Understanding the frequency and types of oral lesions in children is crucial for early diagnosis and management.
Purpose of the Study:
- To determine the prevalence of oral mucosal lesions in a large cohort of children aged 0-12 years.
- To identify the most common types of oral lesions and any associations with gender or underlying health conditions.
Main Methods:
- Retrospective cross-sectional study utilizing clinical charts from January 1997 to December 2007.
- Inclusion of 10,128 children aged 0-12 years.
- Data collection focused on age, gender, and pathological diagnosis, adhering to World Health Organization criteria.
Main Results:
- A prevalence of 28.9% for oral mucosal lesions was observed in the studied pediatric population.
- The most frequent lesions included oral candidiasis (28.4%), tongue lesions (18.5%), and traumatic lesions (17.8%).
- Children with chronic diseases exhibited a significantly higher frequency of oral lesions compared to healthy children (P < .01).
Conclusions:
- Oral mucosal alterations are common in children, affecting a substantial portion of the pediatric population.
- Specific oral disorders may serve as indicators of underlying medical conditions in children.
- Further research into the etiological factors and long-term implications of these lesions is warranted.
Objective:
The exact prevalence of oral lesions in childhood is not well known. We sought to define the prevalence of oral mucosal lesions in a large group of children.
Study Design:
A retrospective cross-sectional study was performed using clinical charts from January 1997 to December 2007. Data collected included age, gender, and pathologic diagnosis.
Results:
In total, 10,128 children (0-12 years old) were enrolled. Clinical diagnostic criteria proposed by the World Health Organization were followed. The frequency of children presenting oral mucosal lesions was 28.9%, and no differences related to gender were observed. The most frequent lesions recorded were oral candidiasis (28.4%), geographic tongue and other tongue lesions (18.5%), traumatic lesions (17.8%), recurrent aphthous ulcerations (14.8%), herpes simplex virus type 1 infections (9.3%), and erythema multiforme (0.9%). Children suffering from chronic diseases had a higher frequency of oral lesions compared with healthy children (chi-square: P < .01).
Conclusion:
Mucosal alterations in children are relatively common, and several oral disorders are associated with underlying medical conditions.
More Related Videos
Related Concept Videos
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Herpes
Poliomyelitis

