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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
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Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
Menopause01:28

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Preventable breast cancer is postmenopausal.

Kari Hemminki1, Asta Försti, Jan Sundquist

  • 1Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany. k.hemminki@dkfz.de

Breast Cancer Research and Treatment
|May 11, 2010
PubMed
Summary

Breast cancer incidence is rising in Western countries. Immigrants from low-risk areas show older incidence patterns, suggesting environmental factors influence breast cancer risk.

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Area of Science:

  • Epidemiology
  • Oncology
  • Public Health

Background:

  • Breast cancer incidence has significantly increased in Western nations.
  • The reasons for this rise, particularly concerning environmental influences, remain unclear.
  • Understanding these factors is crucial for developing effective prevention strategies.

Purpose of the Study:

  • To investigate age-specific breast cancer incidence trends in immigrants relocating to Sweden from low-incidence regions.
  • To compare immigrant breast cancer incidence with that of native Swedes.
  • To identify potential environmental or lifestyle factors contributing to breast cancer etiology.

Main Methods:

  • Utilized the Swedish Family-Cancer Database to calculate standardized incidence ratios (SIRs) for immigrants.
  • Compared age-specific incidence data from low and high incidence populations (Cancer Incidence in Five Continents IX, NORDCAN).
  • Analyzed incidence trends based on country of origin and length of stay in Sweden.

Main Results:

  • Immigrants from seven low-incidence countries had lower SIRs (0.45-0.70) compared to native Swedes.
  • SIRs showed a slight increase with longer duration of stay in Sweden (0.55 to 0.59).
  • Immigrants' age-specific incidence curves resembled older Swedish/Danish rates, with a lower postmenopausal component.

Conclusions:

  • The primary difference in breast cancer incidence between high and low-risk areas lies in postmenopausal cancer, which has risen over the past century.
  • Immigrants from low-risk areas exhibit incidence patterns similar to Swedes from 50 years ago.
  • These findings highlight the role of environmental factors in breast cancer etiology and offer avenues for prevention research.