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Updated: Jun 13, 2026

Viability Assay of Trichoderma stromaticum Conidia Inside Human Peripheral Blood Mononuclear-Derived Macrophages
Published on: October 20, 2023
Translational research on Trichoderma: from 'omics to the field.
Matteo Lorito1, Sheridan L Woo, Gary E Harman
1Dipartimento di Arboricoltura, Botanica e Patologia Vegetale (ArBoPaVe), Università di Napoli Federico II, Portici, Napoli, Italy 80138. lorito@unina.it
Trichoderma fungi are vital biocontrol agents for plant disease. Advanced
Area of Science:
- Agricultural Science
- Microbiology
- Genomics
Background:
- Trichoderma spp. are widely used microbial biocontrol agents with a long history of beneficial effects on plants and soil.
- Genomic and 'omics' approaches are revolutionizing the understanding and application of these fungi.
- Translational research successfully translates 'omics' discoveries into practical agricultural solutions.
Purpose of the Study:
- To review the latest discoveries in Trichoderma genomics, transcriptomics, proteomics, and metabolomics.
- To explore the complex biotic interactions of Trichoderma in natural environments.
- To highlight the agricultural and industrial importance of Trichoderma.
Main Methods:
- Review of structural and functional genomics data.
- Analysis of transcriptomic, proteomic, and metabolomic studies.
- Synthesis of research on Trichoderma biotic interactions and applications.
Main Results:
- 'Omics' studies reveal novel insights into Trichoderma expressome and metabolome.
- Understanding of complex microbial interactions and their role in biocontrol.
- Demonstration of successful translation of 'omics' data into crop management strategies.
Conclusions:
- Trichoderma spp. represent a successful model for translational research in biocontrol.
- 'Omics' technologies are crucial for advancing the use of Trichoderma in agriculture and industry.
- Further research into Trichoderma interactions will yield new applications for sustainable agriculture.
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