Related Experiment Video
Updated: Jun 13, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018
Spindle cell liposarcoma of the face: case report and literature review
T Agostini1, C Catelani, A Acocella
1AOUP Burn Center and Plastic Surgery Unit, Via Paradisa 2, Ospedale Cisanello, 56100 Pisa, Italy. tommasoagostini@ymail.com
Abstract:
Liposarcoma is a common soft tissue sarcoma accounting for approximately 20% of all mesenchymal tumours across all ages. Recently, collaborative research in the specialties of pathology and genetics has led to the delineation of several tumour variants with different behaviours and prognoses, one of which includes the very rare spindle cell liposarcoma (SCL) subtype. We present the first case of an SCL arising in the subcutaneous tissue of the forehead of a 78-year-old man. In light of the rarity of this tumour, we describe the tumour and its clinical and pathological characteristics and undertake a literature review to clarify the surgical management and prognosis of SCL, and increase awareness to avoid misdiagnosis of a benign soft tissue neoplasm.
