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Stroke and dilated cardiomyopathy associated with celiac disease
Murat Doğan1, Erdal Peker, Eren Cagan
1Department of Pediatric Endocrinology, Yuzuncu Yil University, Medical School, 65100 Van, Turkey. doganmurat.md@gmail.com
World Journal of Gastroenterology
|May 12, 2010
Summary
Celiac disease (CD) can cause neurological issues like stroke, even without typical digestive symptoms. This case highlights CD as a potential cause for ischemic stroke in children.
Area of Science:
- Pediatric Neurology
- Gastroenterology
- Cardiology
Background:
- Celiac disease (CD) is an autoimmune disorder triggered by gluten ingestion.
- Neurological manifestations of CD are known, but often occur with gastrointestinal symptoms.
- Rarely, CD may present with severe neurological complications without overt malabsorption.
Observation:
- An 8-year-old girl with CD presented with acute neurological deficits indicative of a stroke.
- She exhibited symptoms including left-sided weakness, failure to thrive, and abdominal distention.
- Physical examination revealed short stature, pallor, and a cardiac murmur.
Findings:
- Brain imaging confirmed an ischemic stroke in the basal ganglia.
- Extensive testing ruled out other common causes of stroke and connective tissue diseases.
- Serological markers and intestinal biopsy confirmed the diagnosis of celiac disease.
Implications:
- This case underscores the importance of considering celiac disease in the differential diagnosis of pediatric ischemic stroke.
- Early diagnosis and management of CD may prevent severe neurological complications.
- Highlights the diverse and sometimes non-classical presentations of celiac disease.
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