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Matrix-enhanced secondary ion mass spectrometry (ME SIMS) using room temperature ionic liquid matrices

Jennifer J D Fitzgerald1, Paul Kunnath, Amy V Walker

  • 1Department of Materials Science and Engineering, University of Texas at Dallas, 800 West Campbell Road, RL 10, Richardson, Texas 75080, USA.

Analytical Chemistry
|May 14, 2010
PubMed
Summary

Room temperature ionic liquids (ILs) show promise as matrices for time-of-flight secondary ion mass spectrometry (TOF-SIMS) and MS imaging. These novel IL matrices significantly enhance molecular ion signals and improve detection limits for various biomolecules.

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