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Updated: Jun 13, 2026

Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
Traditional and emerging antifungal therapies
Tamra M Arnold1, Emily Dotson, George A Sarosi
1Division of Clinical Pharmacy, Roudebush VA Medical Center, Indianapolis, Indiana, USA.
Abstract:
Invasive mycoses continue to be a major problem in the growing population of immunosuppressed patients. More antifungal agents are now available than ever. The options are many, with more efficacies and less toxicity than in the past. These agents differ in terms of spectrum of activity, pharmacologic properties, and indications. In this article we discuss the three major classes of antifungal agents: the polyens, the triazoles, and the echinocandins. The emphasis is placed on their clinical use, side effects, drug interactions, and other practical issues.
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