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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
Published on: May 31, 2020
[Persistence of dengue symptoms in patients in Uberaba, Minas Gerais State, Brazil]
Luciana de Almeida Silva Teixeira1, Juliana Salviano Mendonça Lopes, André Guilherme da Costa Martins
1Universidade Federal do Triângulo Mineiro, Uberaba, Brasil. lalmeidas@dcm.uftm.edu.br
Abstract:
The clinical picture of dengue is characterized by a maximum duration of 14 days despite frequent complaints of longer symptoms. This study evaluated the occurrence of persistent symptoms (> 14 days) and its impact on daily life. A hundred eighteen patients were interviewed, and the main symptoms at diagnosis were mialgia (98.3%), fever (97.5%) and weakness (95.8%). The presence of at least a persistent symptom was related by 77 (65.2%) individuals of wich 10 (8.5%) described it as intense and lasting for 30 days or more. The most persistent symptoms mentioned were weakness (58 cases), hiporexia (49) and sleepiness (40), occurring mostly in women, with odds ratio: 5.4 (IC95%: 2.3-12.3). A significant association between the persistence of the symptoms and the history of extra expenses (p = 0,02) was found, as well as a delay to return to normal activities (p < 0.001). Thus, it was verified that dengue presented a relevant impact on every day life, even after 14 days, a fact wich was associated with the presence of persistent symptoms of the illness.
Insights
Dengue symptoms often persist beyond 14 days, significantly impacting daily life and finances. Persistent weakness, poor appetite, and sleepiness were common, especially in women.
Area of Science:
- Infectious Diseases
- Public Health
- Clinical Medicine
Context:
- Dengue fever is a mosquito-borne viral infection with a typical clinical course of up to 14 days.
- However, patient-reported symptoms frequently extend beyond this period, necessitating further investigation.
Purpose:
- To evaluate the occurrence of dengue symptoms persisting longer than 14 days.
- To assess the impact of these persistent symptoms on patients' daily lives and identify associated factors.
Summary:
- A study of 118 dengue patients found that 65.2% experienced persistent symptoms (>14 days), with 8.5% reporting intense symptoms lasting over 30 days.
- Common persistent symptoms included weakness, poor appetite (hiporexia), and sleepiness, which were more prevalent in women (OR: 5.4).
- A significant association was found between symptom persistence and increased expenses (p=0.02) and delayed return to normal activities (p<0.001).
Impact:
- Dengue significantly impacts daily life beyond the standard 14-day illness duration due to persistent symptoms.
- This prolonged illness can lead to financial strain and delayed recovery, highlighting a critical public health concern.
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