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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Antianginal Drugs: Calcium Channel Blockers and Ranolazine01:25

Antianginal Drugs: Calcium Channel Blockers and Ranolazine

Angina pectoris, a primary symptom of ischemic heart disease, requires careful pharmacological interventions. In this context, calcium channel blockers (CCBs) and ranolazine have emerged as crucial pharmacotherapeutic agents, providing deep insights into the complexities of angina management.
CCBs, a diverse class that includes dihydropyridines (nifedipine) and diphenylalkylamines (verapamil and diltiazem), exert their effect by blocking calcium channels in cardiac and smooth muscle cells. This...
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

[Male osteoporosis].

Zeitschrift fur Rheumatologieยท2016
Same author

The position of strontium ranelate in today's management of osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USAยท2015
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Management of osteoporosis of the oldest old.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USAยท2014
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[Vitamin D deficiency in Germany, is it a danger for increased morbidityand mortality?].

MMW Fortschritte der Medizinยท2013
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Early changes in biochemical markers of bone formation during teriparatide therapy correlate with improvements in vertebral strength in men with glucocorticoid-induced osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USAยท2013
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[Combination of alendronate plus alfacalcidol in the treatment of osteoporosis. Rationale, preclinical data and clinical evidence].

MMW Fortschritte der Medizinยท2013

Related Experiment Video

Updated: Jun 13, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Strontium ranelate: an effective solution for diverse fracture risks.

J D Ringe1

  • 1General Internal Medicine and West-German Osteoporosis Center (WOC), Klinikum Leverkusen, D-51375, Leverkusen, Germany. ringe@klinikum-lev.de

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|May 14, 2010
PubMed
Summary

Strontium ranelate effectively reduces fracture risk in osteoporosis patients. Its efficacy is consistent across diverse patient groups, regardless of sex or osteoporosis cause.

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Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
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Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling

Published on: January 5, 2015

Related Experiment Videos

Last Updated: Jun 13, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
04:19

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
15:11

Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling

Published on: January 5, 2015

Area of Science:

  • Bone biology and metabolic diseases
  • Pharmacology and drug efficacy studies
  • Clinical diagnostics and risk assessment

Background:

  • Osteoporosis is a major global health concern, characterized by weakened bones and increased fracture risk.
  • The clinical presentation of osteoporosis is diverse, necessitating treatments effective across various pathophysiological conditions.
  • Fracture risk assessment, incorporating multiple patient factors, is now central to treatment decisions.

Purpose of the Study:

  • To evaluate the fracture-reducing efficacy of strontium ranelate in osteoporosis.
  • To determine if strontium ranelate's therapeutic benefits are independent of patient sex and osteoporosis etiology.
  • To assess if efficacy is consistent across major diagnostically relevant risk factors.

Main Methods:

  • Review of clinical studies on strontium ranelate in osteoporosis patients.
  • Analysis of fracture reduction data stratified by patient sex and osteoporosis type.
  • Examination of efficacy in relation to established osteoporosis risk factors.

Main Results:

  • Strontium ranelate demonstrated significant fracture risk reduction in osteoporosis.
  • Efficacy was observed consistently across different patient sexes.
  • Therapeutic benefits were maintained irrespective of the underlying cause or specific risk factors for osteoporosis.

Conclusions:

  • Strontium ranelate provides reliable fracture reduction in osteoporosis.
  • The drug's efficacy is not significantly influenced by patient sex, osteoporosis etiology, or key risk factors.
  • This supports strontium ranelate's broad clinical utility in managing osteoporosis.