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Updated: Jun 13, 2026
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Hypertension as a risk factor for migraine chronification
P Barbanti1, C Aurilia, G Egeo
1Headache and Pain Unit, IRCCS San Raffaele Pisana, Via Della Pisana 235, 00163, Rome I, Italy. piero.barbanti@sanraffaele.it
Summary
Arterial hypertension may drive episodic migraine transformation into chronic migraine. Monitoring blood pressure and exploring endothelial function treatments are recommended for migraine patients with increased attack frequency.
Area of Science:
- Neurology
- Cardiovascular Medicine
Background:
- Episodic migraine can progress to chronic migraine.
- Comorbid medical conditions are implicated in migraine transformation.
- Arterial hypertension is increasingly recognized as a factor in chronic migraine development.
Purpose of the Study:
- To investigate the role of arterial hypertension in the transformation of episodic migraine to chronic migraine.
- To explore the potential mechanisms linking hypertension and migraine chronification.
Main Methods:
- Review of existing studies on hypertension and migraine progression.
- Analysis of the proposed pathophysiological links between arterial hypertension, endothelial dysfunction, and cerebral vasculature.
Main Results:
- Hypertension is associated with chronic migraine and may induce migraine chronification.
- Hypertension may exacerbate migraine's vascular effects, worsening endothelial dysfunction in cerebral vasculature.
Conclusions:
- Blood pressure monitoring is advised for migraineurs with unexplained increases in attack frequency.
- Further research is needed to confirm if prophylactic treatments targeting endothelial function can improve migraine outcomes in hypertensive patients.
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