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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...

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Related Experiment Video

Updated: Jun 13, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Rhinitis in the geriatric population.

Jayant M Pinto1, Seema Jeswani

  • 1Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, The University of Chicago, Chicago, IL, USA. jpinto@surgery.bsd.uchicago.edu.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
|May 15, 2010
PubMed
Summary
This summary is machine-generated.

As the US geriatric population grows, rhinitis in older adults will become more common. Further research is needed to understand geriatric rhinitis causes and develop better treatments.

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Published on: September 22, 2023

Area of Science:

  • Geriatric Medicine
  • Otolaryngology
  • Immunology

Background:

  • The US geriatric population is expanding rapidly, projected to reach 20% by 2030.
  • Rhinitis is a common complaint in older adults, significantly impacting their quality of life.
  • Aging influences nasal physiology and inflammatory conditions, contributing to geriatric rhinitis.

Purpose of the Study:

  • To highlight the increasing prevalence of rhinitis in the growing geriatric population.
  • To underscore the need for improved understanding and treatment of geriatric rhinitis.
  • To identify potential pathophysiological mechanisms underlying rhinitis in older adults.

Main Methods:

  • Literature review on geriatric rhinitis prevalence and pathophysiology.
  • Analysis of age-related changes in nasal physiology.
  • Examination of inflammatory processes in elderly patients with rhinitis.

Main Results:

  • Rhinitis presents a significant health burden for older individuals.
  • Pathogenesis likely involves inflammatory conditions and age-related physiological changes.
  • Current treatments may be insufficient for effectively managing geriatric rhinitis.

Conclusions:

  • Geriatric rhinitis is an emerging health concern due to demographic shifts.
  • Enhanced understanding of pathophysiology is crucial for developing targeted therapies.
  • More research is required to improve quality of life for older adults suffering from rhinitis.