Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Transmission of Pathogens01:24

Transmission of Pathogens

Pathogens spread from their reservoirs to susceptible hosts through three main routes: contact transmission, vehicle transmission, and vector transmission. Each route involves distinct mechanisms of transfer.Contact TransmissionThis category includes direct contact, indirect contact, and droplet transmission:Direct contact involves immediate physical interaction between individuals—such as a handshake—which can spread pathogens like Streptococcus pyogenes, the bacterium responsible for...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Refractory and/or Resistant Herpes Simplex Virus Mucocutaneous Infections in Adult Transplantation and Cellular Therapy Patients: A Single-Center Experience.

Cureus·2026
Same author

False-positive HIV-1 RNA detection following obecabtagene autoleucel.

Bone marrow transplantation·2026
Same author

Viral Culture Conversion with use of Remdesivir for Respiratory Syncytial Virus Lower Respiratory Tract Infection.

The Journal of infectious diseases·2026
Same author

Screening and Reactivation of Chagas Disease Among Solid Organ Transplant Candidates and Recipients: A 10-Year Single Center Experience in Florida.

Transplant infectious disease : an official journal of the Transplantation Society·2026
Same author

Mechanistic Insights to Advance Infectious Diseases Practice.

Transplant infectious disease : an official journal of the Transplantation Society·2026
Same author

Allograft Rejection and the Latent HIV Reservoir in Kidney Transplant Recipients with HIV.

The Journal of infectious diseases·2026

Related Experiment Video

Updated: Jun 13, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Infections transmitted by transplantation.

Michele I Morris1, Staci A Fischer, Michael G Ison

  • 1Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL, USA.

Infectious Disease Clinics of North America
|May 15, 2010
PubMed
Summary

Donor-derived infections are a risk in organ and stem cell transplants. This review covers expected and unexpected transmissions, focusing on screening and management strategies for preventing these rare complications.

More Related Videos

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
08:00

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Published on: May 26, 2021

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
05:52

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay

Published on: May 12, 2023

Related Experiment Videos

Last Updated: Jun 13, 2026

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation
11:49

Trans-vivo Delayed Type Hypersensitivity Assay for Antigen Specific Regulation

Published on: May 2, 2013

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
08:00

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis

Published on: May 26, 2021

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay
05:52

Neutrophil Lifespan Extension with CLON-G and an In Vitro Spontaneous Death Assay

Published on: May 12, 2023

Area of Science:

  • Transplantation Medicine
  • Infectious Diseases
  • Immunology

Background:

  • Infections can be transmitted via solid-organ and stem cell transplantation.
  • Donor-derived infections pose a significant risk, categorized as expected or unexpected based on screening protocols.
  • High-profile cases have increased awareness of this rare but serious complication.

Purpose of the Study:

  • To review the epidemiology of donor-derived infections in transplantation.
  • To discuss current screening practices for infectious agents.
  • To outline management strategies for preventing and treating these transmissions.

Main Methods:

  • Review of existing literature on donor-derived infections in transplantation.
  • Analysis of transmission types: expected (e.g., CMV, EBV, toxoplasmosis) and unexpected (e.g., HIV, HCV).
  • Examination of screening protocols and prophylaxis strategies employed globally.

Main Results:

  • Expected transmissions, despite screening, occur with some frequency and are managed with established protocols.
  • Unexpected transmissions, despite negative donor screening, represent a rarer but critical concern.
  • Screening and prophylaxis are standard practices in most transplant centers worldwide.

Conclusions:

  • Donor-derived infections remain a relevant concern in transplantation.
  • Effective screening and prophylaxis are crucial for mitigating risks.
  • Continued vigilance and research are necessary for managing these rare complications.