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Updated: Jun 13, 2026

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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)
Published on: April 21, 2019
[External quality controls for allergy analysis in the Quality Control Center Switzerland from 2006 to 2008]
E Dayer1, D Kesseler, P-A Morandi
1Service de Genétique et Immunologie, Institut Central des Hôpitaux valaisans, 1950 Sions. eric.dayer@ichv.ch
Revue Medicale Suisse
|May 18, 2010
Summary
External quality assessment for immunoglobulin E (IgE) testing in Switzerland demonstrates excellent analytical performance. Since 2006, mandatory IgE controls show high participant success rates, ensuring reliable allergy diagnostics.
Area of Science:
- Clinical chemistry and immunology
- Medical laboratory quality assurance
Context:
- External quality assessment (EQA) is crucial for medical laboratory performance.
- Mandatory EQA for immunoglobulin E (IgE) analysis has been in place in Switzerland since 2006.
- Programs cover total IgE, specific IgE (cat, birch, peanut), and multi-specific IgE.
Purpose:
- To evaluate the analytical performance of IgE testing methods in Switzerland.
- To assess participant proficiency based on established criteria.
- To report on the outcomes of the EQA program from 2006 to 2008.
Summary:
- Data from the Quality Control Center Switzerland (2006-2008) indicate very good analytical results across all methods used.
- A significant number of participants met the criteria for proficiency assessment.
- Successful participants received the QUALAB conformity certificate.
Impact:
- Demonstrates the high quality and reliability of IgE testing in Swiss medical laboratories.
- Validates the effectiveness of the established EQA program.
- Contributes to confidence in allergy diagnosis and patient management through consistent analytical performance.
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