[The effect of collagenous gel on endoprosthesis anchoring.]

Collagen supplemented with tripeptide (gly-his-lys) was tested for implantation of cervicocapital endoprostheses of the hip in adult minipigs. In anaesthesia bone marrow cavity was filled up with the collagenous gel and then one of the two endoprosthesis types, produced by BMT Poldi Kladno was implanted. The experimental animals were killed eight, nine and ten weeks after operation. The femors were removed and roentgenologically and histologically examined. When bone marrow cavity was filled up with collagenous gel, anchoring of endoprosthesis with newly formed tissue was accelerated in comparison with those without gel. In the presence of fatty bone marrow residues healing process was disturbed. It cannot be excluded that this fact might have an effect on long term effective endoprosthesis anchoring. Key words: non-cemented endoprosthesis, collagenous gel, tripeptide (gly-his-lys).