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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...

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Related Experiment Video

Updated: Jun 13, 2026

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

A new shape memory clamp in small bone surgery.

J Musialek1, P Filip

  • 1Ortopedicko-traumatologické oddelení Mestské nemocnice, Ostrava.

Acta Chirurgiae Orthopaedicae Et Traumatologiae Cechoslovaca
|May 18, 2010
PubMed
Summary

New shape memory titanium-nickel (TiNi) alloy clamps offer effective internal fixation for small bone fractures. Clinical evidence from 64 patients confirms their suitability for small bone surgery applications.

Area of Science:

  • Biomaterials Engineering
  • Orthopaedic Surgery
  • Materials Science

Background:

  • Internal fixation of small bone fragments presents unique challenges.
  • Development of novel fixation devices is crucial for improving surgical outcomes.
  • Shape memory alloys offer unique properties for medical applications.

Purpose of the Study:

  • To investigate and manufacture a novel internal fixative using a titanium-nickel (TiNi) alloy with shape memory properties.
  • To evaluate the efficacy and safety of TiNi memory clamps in small bone surgery.

Main Methods:

  • Systematic study and development of TiNi alloy substructure for optimized clamp parameters.
  • Preclinical animal experiments to validate the application philosophy.
  • Clinical evaluation involving 64 patients, including radiological and histological assessments.

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Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
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Last Updated: Jun 13, 2026

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An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
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10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

Main Results:

  • Successful manufacturing of shape memory TiNi clamps with optimized parameters.
  • Positive outcomes from animal experiments supporting the use of TiNi clamps.
  • Preclinical, clinical, radiological, and histological evidence from 64 patients demonstrated the clamps meet theoretical and practical demands.

Conclusions:

  • The developed TiNi memory clamps are a viable and effective solution for small bone fragment osteosynthesis.
  • The clamps satisfy contemporary theoretical requirements and practical needs in orthopaedic surgery.
  • This innovation represents a significant advancement in internal fixation devices for small bone fractures.